Dystonia
is a neurological movement disorder characterized by sustained muscle
contractions, abnormal muscle tension, and involuntary, painful muscle
contractions. Statistics indicate that over 300,000 people in North America are
affected by this disorder that is the third most common movement disorder after
Parkinson's disease and nerve tremors. These involuntary and sometimes painful
movements may affect either a single muscle or an entire group of muscles like
those in the arms, neck, or legs or even the entire body. People afflicted with
dystonia usually have no associated psychiatric disorders and they have normal
intelligence. Marijuana
Effects
A
few preclinical studies and case reports investigating the use of medical
cannabis to control the symptoms of dystonia, primarily these twisting and
repetitive movements or abnormal postures are now available in recently
published scientific literature. The July issue of The Journal of Pain and
Symptom Management carries a 2002 case study that reports an improvement in the
symptoms of dystonia after a 42 year old patient suffering from chronic pain
smoked medical marijuana. It was reported by investigators and medical
researchers that the pain score (subjectively) dropped from a high 9 to nothing
(considering a 0-10 analog visual scale of pain) after the patient inhaled MMJ.
Additionally, the subject did not need additional analgesic medication for the
next forty eight hours. Marijuana Medical
Investigators
concluded that there were no existing treatment plan or intervention to date
that has produced such an overall dramatic improvement in the condition of
patient's like these. The same results were obtained in a case study that was
conducted on another 25 year old patient who was suffering from Wilson's
disease that triggered generalized dystonia. In the August 2004 issue of the
journal Movement Disorders, an Argentinian research team documented their
findings of the patient exhibiting significant clinical improvement after the
inhalation of medical cannabis. In the same year, a team of German researchers
at the Hannover Medical School administered 5 mg of the active cannabinoid in
medical marijuana called THC to a 38-year-old professional pianist. Marijuana Vaporizer
The
musician's dystonia was successfully treated following the administration of a
single dose of THC in this placebo controlled trial. Researchers reported that
prior to cannabinoid treatment; the patient was unresponsive to standard
medications and therefore, was no longer even performing publicly. However,
there was a clear improvement of motor control in the affected hand of the
subject and the patient was also able to play technically demanding and complex
literature just two hours after the intake of THC. The subject was not able the
play the same pieces of music before the treatment process. These results
clearly indicate that medical cannabis significantly alleviates the symptoms of
this type of dystonia called focal dystonia. Medical Marijuana
In
2002, a placebo-controlled randomized study that investigated the use of
Cesamet (a synthetic oral cannabinoid naboline) in 15 patients afflicted with
segmental primary and generalized dystonia showed no significant improvement in
their condition. Investigators concluded that this outcome may be dose related
and it has nothing to do with the efficacy of medical cannabis in helping
patients cope with their dystonia symptoms. High doses of the natural
non-psychoactive CBD (cannabinoid cannabidiol) and synthetic cannabinoids are
known to moderate the progression of the disease in animals as indicated by at
least one recent preclinical trial and further investigation regarding the use
of cannabis and cannabinoids in humans is underway. Quality Marijuana
No comments:
Post a Comment